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Comprehensive safety studies spanning six months in rats (up to 100 mg/kg/day) and nine months in cynomolgus monkeys (up to 50 mg/kg/day) revealed no adverse findings, with NOAEL reaching the highest applied dosages

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The right question is what the injury picture looks like and which compound matches that picture

You may be finding that a previously enjoyable walk is becoming shorter, that golf or cycling is less comfortable, or that work and family life are affected by pain after activity